{"id":245,"date":"2025-05-26T01:28:36","date_gmt":"2025-05-26T08:28:36","guid":{"rendered":"https:\/\/www.lechengmedical.com\/?p=245"},"modified":"2025-05-26T01:28:36","modified_gmt":"2025-05-26T08:28:36","slug":"breakthrough-in-spinal-cord-injury-treatment-shize-biotechs-universal-ipsc-derived-cell-therapy-enters-global-clinical-trials","status":"publish","type":"post","link":"https:\/\/www.lechengmedical.com\/zh\/breakthrough-in-spinal-cord-injury-treatment-shize-biotechs-universal-ipsc-derived-cell-therapy-enters-global-clinical-trials\/","title":{"rendered":"\u810a\u9ad3\u635f\u4f24\u6cbb\u7597\u53d6\u5f97\u7a81\u7834\uff1aShize Biotech\u7684\u901a\u7528\u578biPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5\u8fdb\u5165\u5168\u7403\u4e34\u5e8a\u8bd5\u9a8c"},"content":{"rendered":"

<\/p>\n

\u810a\u9ad3\u635f\u4f24\uff1a\u5168\u7403\u533b\u5b66\u6311\u6218<\/h2>\n

\n\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u662f\u4e00\u79cd\u4e25\u91cd\u7684\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\uff0c\u5176\u7279\u5f81\u662f\u8fd0\u52a8\u548c\u611f\u89c9\u529f\u80fd\u6c38\u4e45\u6027\u53d7\u635f\uff0c\u901a\u5e38\u4f1a\u5bfc\u81f4\u762b\u75ea\u3002\u5e38\u89c1\u75c5\u56e0\u5305\u62ec\u521b\u4f24\uff08\u4f8b\u5982\u4e8b\u6545\u6216\u8dcc\u5012\uff09\u548c\u9000\u884c\u6027\u75be\u75c5\u3002\u60a3\u8005\u53ef\u80fd\u51fa\u73b0\u80a2\u4f53\u90e8\u5206\u6216\u5b8c\u5168\u4e27\u5931\u6d3b\u52a8\u80fd\u529b\u3001\u8180\u80f1\/\u80a0\u9053\u529f\u80fd\u969c\u788d\u548c\u6162\u6027\u75bc\u75db\uff0c\u5e76\u4e14\u7ec8\u751f\u9700\u8981\u4f9d\u8d56\u5eb7\u590d\u548c\u62a4\u7406\u3002.<\/p>\n

\u5168\u7403\u8303\u56f4\u5185\uff0c\u5927\u7ea6 1500\u4e07\u4eba<\/strong> \u60a3\u6709\u810a\u9ad3\u635f\u4f24\uff0c\u5305\u62ec\u8d85\u8fc7 \u4e2d\u56fd\u6709300\u4e07\u4eba<\/strong>, \uff0c \u5728\u54ea\u91cc \u65b0\u589e10\u4e07\u4f8b<\/strong> \u6bcf\u5e74\u90fd\u6709\u76f8\u5173\u62a5\u544a\u3002\u793e\u4f1a\u7ecf\u6d4e\u8d1f\u62c5\u5de8\u5927\uff1a\u5728\u9ad8\u6536\u5165\u56fd\u5bb6\uff0c\u6bcf\u4f4d\u60a3\u8005\u7ec8\u751f\u533b\u7597\u4fdd\u5065\u8d39\u7528\u8d85\u8fc7100\u4e07\u82f1\u9551\uff0c\u518d\u52a0\u4e0a\u52b3\u52a8\u529b\u53c2\u4e0e\u7387\u4e0b\u964d\u548c\u5fc3\u7406\u5065\u5eb7\u6311\u6218\uff0c\u60c5\u51b5\u66f4\u52a0\u590d\u6742\u3002.<\/p>\n

\n

\u65bd\u6cfd\u751f\u7269\uff1a\u5f00\u521b\u901a\u7528\u578biPSC\u884d\u751f\u7ec6\u80de\u7597\u6cd5<\/h2>\n

\u8be5\u516c\u53f8\u7531\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\u9886\u57df\u7684\u8d44\u6df1\u4e13\u5bb6\u674e\u7fd4\u535a\u58eb\u4e8e2021\u5e74\u521b\u7acb\u3002 \u5e72\u7ec6\u80de<\/a> (iPSC) \u7814\u7a76\uff0c, \u65bd\u6cfd\u751f\u7269\u79d1\u6280<\/strong> \u82cf\u5dde\u751f\u7269\u6280\u672f\u6709\u9650\u516c\u53f8\u5df2\u6210\u4e3a\u5f00\u53d1\u7528\u4e8e\u6cbb\u7597\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u75be\u75c5\u7684\u201c\u73b0\u6210\u201d\u5f02\u4f53\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u884d\u751f\u7ec6\u80de\u7597\u6cd5\u7684\u9886\u5148\u4f01\u4e1a\u3002\u8be5\u516c\u53f8\u81f4\u529b\u4e8e\u6cbb\u7597\u5e15\u91d1\u68ee\u75c5\u3001\u808c\u840e\u7f29\u4fa7\u7d22\u786c\u5316\u75c7\uff08ALS\uff09\u548c\u810a\u9ad3\u635f\u4f24\uff08SCI\uff09\u7b49\u6cbb\u7597\u9009\u62e9\u6709\u9650\u7684\u75be\u75c5\u3002.<\/p>\n

\u73b0\u6210\u7684iPSC\u884d\u751f\u795e\u7ecf\u7956\u7ec6\u80de\u7597\u6cd5<\/h3>\n

Shize\u7684\u65d7\u8230\u4ea7\u54c1\u5229\u7528\u4e86 \u4e34\u5e8a\u7ea7\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de<\/strong> \u5206\u5316\u4e3a\u4e9a\u578b\u7279\u5f02\u6027\u795e\u7ecf\u7956\u7ec6\u80de\u3002\u8fd9\u4e9b\u7ec6\u80de\u65e8\u5728\u66ff\u4ee3\u53d7\u635f\u795e\u7ecf\u5143\uff0c\u4fc3\u8fdb\u795e\u7ecf\u518d\u751f\uff0c\u5e76\u6062\u590d\u810a\u9ad3\u635f\u4f24\u60a3\u8005\u7684\u529f\u80fd\u8fde\u63a5\u3002\u4e34\u5e8a\u524d\u7814\u7a76\u5df2\u5728\u52a8\u7269\u6a21\u578b\u4e2d\u8bc1\u5b9e\u4e86\u5176\u7597\u6548\uff0c\u8868\u73b0\u4e3a\u8fd0\u52a8\u529f\u80fd\u6062\u590d\u6539\u5584\u548c\u708e\u75c7\u51cf\u8f7b\u3002.<\/p>\n

\u4e34\u5e8a\u8fdb\u5c55\u548c\u76d1\u7ba1\u91cc\u7a0b\u7891<\/h3>\n

2025\u5e745\u6708\uff0cShize\u83b7\u5f97\u4e86\u4e2d\u56fd\u56fd\u5bb6\u836f\u54c1\u76d1\u7763\u7ba1\u7406\u5c40\uff08NMPA\uff09\u548c\u7f8e\u56fdFDA\u7684\u6279\u51c6\uff0c\u542f\u52a8\u4e86\u8be5\u9879\u76ee\u3002 I\/II\u671f\u8bd5\u9a8c<\/strong> \u7528\u4e8e\u810a\u9ad3\u635f\u4f24\u6cbb\u7597\u2014\u2014\u8fd9\u662fiPSC\u884d\u751f\u7597\u6cd5\u5728\u8be5\u9002\u5e94\u75c7\u9886\u57df\u7684\u5168\u7403\u9996\u4f8b\u3002\u8be5\u7597\u6cd5\u4e0e\u4e2d\u5c71\u5927\u5b66\u9644\u5c5e\u7b2c\u4e09\u533b\u9662\u7b49\u9876\u5c16\u533b\u9662\u5408\u4f5c\uff0c\u65e8\u5728\u8bc4\u4f30\u5176\u5728\u6025\u6027\u81f3\u4e9a\u6025\u6027\u635f\u4f24\u60a3\u8005\u4e2d\u7684\u5b89\u5168\u6027\u548c\u6709\u6548\u6027\u3002\u8fd9\u5efa\u7acb\u5728\u4e4b\u524d\u7684\u6210\u529f\u4e4b\u4e0a\uff1a2023\u5e74\uff0c\u4ed6\u4eec\u7684ALS\u7597\u6cd5\u6210\u4e3a\u2026\u2026 \u4e2d\u56fd\u9996\u4e2aiPSC\u884d\u751f\u836f\u7269<\/strong> \u83b7\u5f97 FDA \u5b64\u513f\u836f\u8d44\u683c\u8ba4\u5b9a\uff0c\u83b7\u6279\u540e\u4eab\u6709 7 \u5e74\u5e02\u573a\u72ec\u5360\u6743\u3002.<\/p>\n<\/section>\n

\n

\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u6cbb\u7597\u9886\u57df\u7684\u521b\u65b0\u4f20\u627f<\/h2>\n

\u81ea\u6210\u7acb\u4ee5\u6765\uff0cShize \u4e00\u76f4\u81f4\u529b\u4e8e\u514b\u670d\u4e2d\u67a2\u795e\u7ecf\u7cfb\u7edf\u836f\u7269\u7814\u53d1\u7684\u72ec\u7279\u6311\u6218\u3002\u4e3b\u8981\u6210\u5c31\u5305\u62ec\uff1a<\/p>\n

    \n
  • 2021\u20132023\uff1a<\/strong> \u5efa\u7acb\u4e86 5,000 \u5e73\u65b9\u7c73\u7684\u7814\u53d1\u548c GMP \u8bbe\u65bd\uff0c\u5b9e\u73b0\u4e86\u4e34\u5e8a\u7ea7 iPSC \u7cfb\u7684\u89c4\u6a21\u5316\u751f\u4ea7\u3002.<\/li>\n
  • 2024:<\/strong> \u5b8c\u6210\u4e86\u4e2d\u56fd\u9996\u4e2a\u5e15\u91d1\u68ee\u75c5\u56fd\u5bb6\u7533\u62a5\u4e34\u5e8a\u7814\u7a76\uff0c\u8bc1\u660e\u60a3\u8005\u5728 12 \u4e2a\u6708\u5185\u75c7\u72b6\u6301\u7eed\u6539\u5584\u3002.<\/li>\n
  • 2025:<\/strong> \u516c\u53f8\u5df2\u5c06\u5176\u7814\u53d1\u7ba1\u7ebf\u6269\u5c55\u81f3\u4e94\u79cd\u5728\u7814\u7597\u6cd5\uff0c\u6240\u6709\u7597\u6cd5\u5747\u6b63\u5728\u63a5\u53d7\u4e2d\u7f8e\u53cc\u91cd\u76d1\u7ba1\u5ba1\u6279\u3002.<\/li>\n<\/ul>\n

    \u5728\u77e5\u540d\u6295\u8d44\u8005\uff08\u5982\u7ea2\u6749\u8d44\u672c\u3001\u793c\u6765\u4e9a\u6d32\u98ce\u9669\u6295\u8d44\u516c\u53f8\uff09\u7684\u652f\u6301\u4e0b\uff0cShize \u4f53\u73b0\u4e86\u4e2d\u56fd\u5728\u5c16\u7aef\u751f\u7269\u6280\u672f\u9886\u57df\u65e5\u76ca\u589e\u957f\u7684\u5f71\u54cd\u529b\uff0c\u5c06\u5b66\u672f\u4e25\u8c28\u6027\u4e0e\u4ea7\u4e1a\u89c4\u6a21\u5316\u76f8\u7ed3\u5408\u3002.<\/p>\n<\/section>\n

    \n

    \u7ed3\u8bba\uff1a\u8fc8\u5411\u518d\u751f\u533b\u5b66\u7684\u65b0\u65f6\u4ee3<\/h2>\n

    \u65bd\u6cfd\u751f\u7269\u7684\u810a\u9ad3\u635f\u4f24\u7597\u6cd5\u4ee3\u8868\u7740\u4e00\u79cd\u8303\u5f0f\u8f6c\u53d8\u2014\u2014\u4ece\u59d1\u606f\u6cbb\u7597\u8f6c\u5411\u518d\u751f\u4fee\u590d\u3002\u5c3d\u7ba1\u4ecd\u5b58\u5728\u6311\u6218\uff08\u4f8b\u5982\uff0c\u957f\u671f\u5b89\u5168\u6027\u3001\u514d\u75ab\u76f8\u5bb9\u6027\uff09\uff0c\u4f46\u4ed6\u4eec\u7684\u8fdb\u5c55\u51f8\u663e\u4e86\u8bf1\u5bfc\u591a\u80fd\u5e72\u7ec6\u80de\uff08iPSC\uff09\u6280\u672f\u5728\u6ee1\u8db3\u795e\u7ecf\u75c5\u5b66\u9886\u57df\u672a\u88ab\u6ee1\u8db3\u7684\u9700\u6c42\u65b9\u9762\u7684\u5de8\u5927\u6f5c\u529b\u3002\u968f\u7740\u4e34\u5e8a\u8bd5\u9a8c\u7684\u63a8\u8fdb\uff0c\u5168\u7403\u533b\u5b66\u754c\u5bc6\u5207\u5173\u6ce8\u7740\u8fd9\u4e00\u8fdb\u5c55\uff0c\u5e76\u671f\u76fc\u7740\u762b\u75ea\u4e0d\u518d\u662f\u7ec8\u8eab\u75be\u75c5\u7684\u672a\u6765\u3002.<\/p>\n<\/section>","protected":false},"excerpt":{"rendered":"

    Explore Shize Biotech’s breakthrough in spinal cord injury treatment with universal iPSC-derived neural progenitor cell therapy entering global Phase I\/II trials. Discover how this regenerative medicine innovation aims to restore motor function and redefine SCI care.<\/p>","protected":false},"author":3,"featured_media":246,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_joinchat":[],"footnotes":""},"categories":[2],"tags":[46,67,85,97,104],"class_list":["post-245","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-breakthroughs","tag-global-clinical-trials","tag-ipsc-derived-cell-therapy","tag-neural-progenitor-cells","tag-regenerative-medicine","tag-spinal-cord-injury-treatment"],"_links":{"self":[{"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/posts\/245","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/users\/3"}],"replies":[{"embeddable":true,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/comments?post=245"}],"version-history":[{"count":0,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/posts\/245\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/media\/246"}],"wp:attachment":[{"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/media?parent=245"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/categories?post=245"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.lechengmedical.com\/zh\/wp-json\/wp\/v2\/tags?post=245"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}